Among people being treated for hypertension (high blood pressure),
those with gum disease had average blood pressure readings 2 to 3
mmHg (milligrams of mercury) higher than those without gum disease
and were less likely to have their pressure under control with
medication.
"Recent literature suggests that poor oral health is associated with
several highly prevalent conditions, such as cardiovascular
diseases, diabetes, stroke, and obesity, and that it is related with
increased mortality," Dr. Davide Pietropaoli from the San Salvatore
Hospital, University of L'Aquila, in Italy told Reuters Health.
"However, what we didn't know and surprises us is that a condition
known as periodontal disease can affect the efficacy of medications
for high blood pressure."
The researchers analyzed data from the annual U.S. National Health
and Nutrition Examination Survey between 2009 and 2014 on adults
over age 30 with hypertension who underwent a dental exam, including
3,626 who said they were currently taking medication to control high
blood pressure and 460 who said they were not.
Based on the dental exams, about 52 percent of participants had
periodontal disease, a chronic inflammation of the tissue around the
roots of teeth, which has also been linked to higher inflammation
throughout the body, the researchers note in the journal
Hypertension. Most of those with gum disease had moderately-severe
cases, about 3 percent had mild disease and 12 percent had severe
gum disease.
Average systolic blood pressure - the pressure exerted on blood
vessel walls when the heart pumps, and typically the first number in
a blood pressure reading - increased progressively from mild to
moderate to severe periodontal disease, researchers found.
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Overall, people with hypertension and periodontal disease were 20
percent more likely than those without gum disease to have their
hypertension uncontrolled with medication.
In addition, blood pressure control was worse in patients with
periodontal disease across all age ranges.
Among hypertensive patients not taking blood pressure medications,
systolic blood pressure averaged 2.8 to 7.6 mmHg higher in the
presence of periodontitis, although periodontal disease did not seem
to increase their risk of having blood pressure above 130/80 mmHg
(the threshold for treatment).
The study wasn't a controlled experiment designed to prove whether
or how gum disease or the inflammation it creates might directly
affect blood pressure.
"If our results are confirmed by dedicated trials, oral health could
improve the treatment of hypertension, which is considered the most
important risk factor for cardiovascular diseases," Pietropaoli said
in an email. "Patients with treated high blood pressure may benefit
from a dedicated program for the reduction of oral inflammation from
periodontal disease by referring to a dentist or periodontist."
The researchers also suggest that periodontal therapy, together with
lifestyle measures (exercise, healthy diet, and so on), could help
to lower blood pressure and possibly limit the need for high blood
pressure medications.
SOURCE: https://bit.ly/2z2tLrA Hypertension, online October 22,
2018.
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