The Argentine re-fractured his kneecap during
the Queen's Club Championships in June in the latest setback to
his injury- plagued career.
The world number 12 missed Wimbledon after scans revealed he had
fractured his right patella and he underwent surgery.
Since his triumph at Flushing Meadows Del Potro, 30, has had
three left wrist surgeries and another to his right wrist but he
has fought back each time to return to the tour.
He reached last year's U.S. Open final and won the 2018 Masters
1000 event at Indian Wells but has said the knee injury could
mean the end of his career.
Del Potro will be replaced in the main draw at Flushing Meadows
by American Denis Kudla.
(Reporting by Rory Carroll)
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