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 For the study, researchers examined data on blood sugar levels for
5,786 people ages 12 to 34 who hadn't been diagnosed with diabetes.
Overall, 18% of the younger people in the study, ranging in age from
12 to 18 years old, had "prediabetes," as did 24% of the adults 19
to 34 years old.
"Prediabetes is highly prevalent in U.S. adolescents and young
adults, especially in male individuals and in people with obesity,"
lead study author Linda Andes of the U.S. Centers for Disease
Control and Prevention in Atlanta and colleagues write in JAMA
Pediatrics.
These teens and young adults with prediabetes are at increased risk
not only for developing type 2 diabetes - the common form of the
disease associated with obesity and aging - but also cardiovascular
problems that can lead to heart attacks and strokes, the study team
writes.
"These findings together with the observed increase in the
prevalence of type 2 diabetes in U.S. adolescents and in
diabetes-related complications in young adults highlight the need
for ... prevention efforts tailored to the young segment of the U.S.
population," the study team notes.
Average blood sugar levels over the course of about three months can
be estimated by measuring a form of hemoglobin that binds to glucose
in blood, known as A1c. Hemoglobin A1c levels of 6.5% or above
signal diabetes.
Levels between 5.7% and 6.4% are considered elevated, though not yet
diabetic, while 5.7% or less is considered normal.
Overall, 5.3% of teens and 8% of young adults in the study had
levels in this "prediabetic" range, the study found.
To get a more complete picture of how many young people might be at
risk for developing full-blown diabetes, researchers also looked at
other things including so-called insulin resistance, or the body's
failure to respond normally to the hormone insulin. Diabetes can
develop when the body can't properly use insulin to convert blood
sugar into energy.
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They also looked at what's known as impaired fasting glucose, when
blood sugar levels are above a normal range but not quite high
enough to formally diagnose diabetes.
Both teens and young adults in the study who appeared to have
prediabetes had higher cholesterol and blood pressure and more fat
stored around their midsections than individuals without
prediabetes.
Among teens in the study, about 23% of males had prediabetes,
compared with 13% of females. Differences persisted among young
adults: 29% of males and 19% of females had prediabetes.
And, less than 16% of white teens had prediabetes, compared with
more than 22% of black and Hispanic adolescents. This difference
also carried through to early adulthood: about 21% of white people
had prediabetes compared with 27% of black individuals and 29% of
Hispanic young adults.
People with obesity were also most likely to have prediabetes: 26%
of teens and 37% of young adults with obesity had this condition.
The study wasn't a controlled experiment designed to prove whether
or how markers of prediabetes might directly lead to diabetes in
teens or young adults.
One limitation of the study is that researchers only had data to
assess prediabetes at a single point in time, the study authors
note.
SOURCE: http://bit.ly/37YCWKo JAMA Pediatrics, online December 2,
2019.
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