| 
			
			 Lilly, along with other major insulin makers, Sanofi SA and Novo 
			Nordisk, has been under mounting pressure from patients and 
			politicians over the rising cost of the life-sustaining diabetes 
			treatment. 
 "While it's still a proposal, we see this as ... a win for patients, 
			lowering their out-of-pocket costs at the pharmacy counter with the 
			greatest benefit realized by patients taking more highly-rebated 
			products such as insulin," Chief Executive David Ricks said on a 
			call with analysts.
 
 Drugmakers argue they have to keep prices high because of the 
			rebates they must pay to pharmacy benefit managers and health 
			insurers to get products on their lists of covered drugs. In 
			January, the administration of U.S. President Donald Trump proposed 
			a rule that would end the rebate system or pass along the savings to 
			patients.
 
			
			 
			"We'll adapt to whatever rules come out and how they get finalized,” 
			Ricks said.
 
 Lilly on Wednesday also cut its 2019 profit and revenue forecasts to 
			account for disappearing sales of its cancer drug Lartruvo, which 
			won conditional U.S. approval in 2016 based on early data but last 
			month failed to extend patient survival a confirmatory trial. Costs 
			related to Lilly's pending $8 billion acquisition of Loxo Oncology 
			also contributed to the revised forecast.
 
 Lilly has said it is suspending promotion of Lartruvo and it will no 
			longer be prescribe to new U.S. patients.
 
			
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			The Indianapolis-based drugmaker's research and development spending 
			is also expected to rise as it develops Loxo's pipeline of targeted 
			drugs for cancers driven by rare genetic mutations.
 The company said it now expects 2019 adjusted earnings of $5.55 to 
			$5.65 per share, down from its prior forecast of $5.90 to $6.00. It 
			expects revenue of $25.1 billion to $25.6 billion versus its prior 
			view of $25.3 billion to $25.8 billion.
 
			"The forecast cut was generally expected, given the Loxo acquisition 
			and the Lartruvo failure were known events," Edward Jones analyst 
			Ashtyn Evans said.
 "Diabetes will always be an area where we'll see pricing pressure. 
			Lilly fully takes that into consideration when giving guidance," she 
			added.
 
 Excluding items, Lilly earned $1.33 per share, a penny shy of 
			analysts' average estimate, according to IBES data from Refinitiv.
 
 Eli Lilly shares fell 1.3 percent to $118.82.
 
 (Reporting by Manogna Maddipatla, Tamara Mathias in Bengaluru and 
			Julie Steenhuysen in Chicago; Editing by Saumyadeb Chakrabarty and 
			Bill Berkrot)
 
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