The project, launched by Britain's Wellcome Trust global health
charity on Thursday, aims both to improve the world's supply of
antivenoms - the only current treatment for snakebites - and to
develop new and more effective drugs for the future.
"Snakebite treatment is essentially reliant on a 100-year-old
process," said David Lalloo, a professor and director of Britain's
Liverpool School of Tropical Medicine.
A dire lack of funding for scientific research has severely limited
progress in this field of medicine, leaving thousands to die
unnecessarily, Lalloo told reporters at a briefing.
Philip Price, a specialist in snakebite science at Wellcome, said
venomous snakebites kill around 120,000 people a year - mostly in
the poorest communities of rural Africa, Asia and South America -
and called it a "hidden health crisis".
Another 400,000 suffer life-changing injuries such as amputations,
which can push already deprived families into even greater poverty,
he told the briefing.
The World Health Organization (WHO) is due later this month to
publish a "Snakebite Roadmap" that will aim to halve deaths and
disability from snakebites by 2030.
The current treatments - antivenoms - are manufactured by injecting
horses with small and relatively harmless amounts of snake venom and
then harvesting their blood to use in treating humans – a 19th
century technology with no common safety or efficacy standards.
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The technique also carries high risks of contamination and side
effects, expert say, and means victims must be treated in hospitals,
sometimes far from the rural settings where most bites occur.
Treatment is often too expensive for victims to afford, and often it
is administered too late to save lives.
Added to these problems, there is a shortage of antivenoms that will
work for the populations most at risk. In Africa, for example, up to
90 percent of antivenoms available could be ineffective.
Mike Turner, Wellcome's director of science, said there was a clear
and urgent need for progress.
"Snakebite is - or should be - a treatable condition," he said.
"While people will always be bitten by venomous snakes, there is no
reason so many should die."
(Reporting by Kate Kelland; Editing by Frances Kerry)
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