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			 But the January sales meeting in a luxury Singapore hotel was far 
			from auspicious. 
			 
			Someone seated in the room, or in the vicinity of the hotel that is 
			renowned for its central location and a racy nightclub in the 
			basement, was about to take coronavirus global. 
			 
			Three weeks later, global health authorities are still scrambling to 
			work out who carried the disease into the mundane meeting of a firm 
			selling gas meters, which then spread to five countries from South 
			Korea to Spain, infecting over a dozen people. 
			 
			Experts say finding this so-called "patient zero" is critical for 
			tracing all those potentially exposed to infection and containing 
			the outbreak, but as time passes, the harder it becomes. 
			 
			"We do feel uncomfortable obviously when we diagnose a patient with 
			the illness and we can't work out where it came from...the 
			containment activities are less effective," said Dale Fisher, chair 
			of the Global Outbreak Alert and Response Network coordinated by the 
			World Health Organisation. 
			
			  
			 
			 
			Authorities initially hinted at Chinese delegates, which included 
			someone from Wuhan - the Chinese city at the epicentre of the virus 
			that has killed over 1,350 people. But a Servomex spokesperson told 
			Reuters its Chinese delegates had not tested positive. 
			 
			Fisher and other experts have compared the Singapore meeting to 
			another so-called "super-spreading" incident at a Hong Kong hotel in 
			2003 where a sick Chinese doctor spread Severe Acute Respiratory 
			Syndrome around the world. 
			 
			The WHO has opened an investigation into the Singapore incident, but 
			said its "way too early" to tell if it is a super-spreading event. 
			 
			SCARY AND SOBERING 
			 
			It was more than a week after the meeting - which according to a 
			company e-mail included Servomex's leadership team and global sales 
			staff - that the first case surfaced in Malaysia. 
			 
			The incubation period for the disease is up to 14 days and people 
			may be able to infect others before symptoms appear. 
			 
			The firm said it immediately adopted "extensive measures" to contain 
			the virus and protect employees and the wider community. Those 
			included self-isolation for all 109 attendees, of whom 94 were from 
			overseas and had left Singapore. 
			 
			But the virus kept spreading. 
			 
			Two South Korean delegates fell sick after sharing a buffet meal 
			with the Malaysian, who also passed the infection to his sister and 
			mother-in-law. Three of the firm's Singapore attendees also tested 
			positive. 
			 
			Then cases started appearing in Europe. 
			 
			An infected British delegate had headed from the conference to a 
			French ski resort, where another five people fell ill. Another 
			linked case then emerged in Spain, and when the Briton returned to 
			his home town in the south of England the virus spread further. 
			
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			"It feels really scary that one minute it's a story in China... and 
			then the next minute it is literally on our doorstep," said Natalie 
			Brown, whose children went to the same school as the British 
			carrier. The school said in a letter that two people at the school 
			had been isolated. 
			"It's scary and sobering how quickly it seems to have spread," said 
			Brown. 
			 
			TIME RUNNING OUT 
			 
			Back in Singapore, authorities were battling to keep track of new 
			cases of local transmissions, many unlinked to previous cases. 
			 
			Management at the hotel - the Grand Hyatt Singapore - said they had 
			cleaned extensively and were monitoring staff and guests for 
			infection but did not know "how, where or when" conference attendees 
			were infected. The lion dancers, who posted photos of the event on 
			Facebook, said they were virus free. 
			"Everyone assumes it was a delegate but it could have been a 
			cleaner, it could have been a waiter," said Paul Tambyah, an 
			infectious diseases expert at National University Singapore. He 
			added it was "very important" to find "patient zero" to establish 
			other possible "chains of transmission". 
			 
			But time may be running out. 
			 
			Singapore health ministry's Kenneth Mak said the government will 
			continue to try and identify the initial carrier until the outbreak 
			ends, but as days pass it will get harder. 
			 
			"We might never be able to tell who that first patient is," Mak 
			said. 
			 
			Meanwhile, the fallout from the conference continues to sow 
			trepidation weeks after the event and thousands of miles away. 
			  
			  
			Reuters visited Servomex's offices in the suburbs of South Korea's 
			capital, Seoul. It was closed and dark inside, and a building guard 
			told Reuters employees were working from home. 
			 
			A notice posted by building management stated a coronavirus patient 
			had entered the complex, while several young women could be 
			overheard in a nearby elevator discussing whether it had been used 
			by the infected person. 
			 
			"Do you think the patient would have gotten on this elevator or the 
			other one?" one said. 
			 
			(Reporting by John Geddie, Joe Brock and Keith Zhai in Singapore, 
			Sangmi Cha and Josh Smith in Seoul, Kate Holton in London, and 
			Joseph Sipalan in Kuala Lumpur; Editing by Raju Gopalakrishnan) 
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