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 The study, among the first analyses in China combing different
COVID-19 vaccines, comes as the country said it would use booster
shots in specific groups amid concerns over vaccines' waning
protection over time.
Participants who received a CanSinoBIO booster dose three to six
months after a second Sinovac shot showed a 78-fold jump on average
in neutralizing antibody levels two weeks later, according to a
paper published on Monday before a peer review.
By contrast, those who received a Sinovac booster shot showed a
15.2-fold increase in neutralizing antibody levels, researchers from
local disease control authorities, CanSinoBIO and other Chinese
institutions said in the paper.
One dose of Sinovac followed by a CanSinoBIO booster at intervals of
one or two months led to a 25.7-fold increase in neutralising
antibody levels, while two doses of Sinovac induced a 6.2-fold
increase.
The study analysed data from about 300 healthy adults aged 18-59.
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 The study did not assess the
boosters' protection against COVID-19 and did
not test the neutralising antibody against the
more transmissible Delta variant, the paper
said.
More than 1.4 billion doses of the Sinovac
vaccine have been administered globally, about
three quarters of them in China.
 China, which has kept local infections under
control, has fully vaccinated around 69% of its
population as of Sept. 6. It said on Tuesday a
total of 2.1 billion doses had been administered
as of Monday.
(Reporting by Roxanne Liu and Ryan Woo; Editing
by Miyoung Kim and Susan Fenton)
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