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'Lucky loser' Roman Safiullin replaced the Norwegian in the draw
and will take on Slovak Alex Molcan later on Tuesday.
"Two days ago in practice I rolled or twisted my ankle," said
Ruud. "I tried everything I could to be ready, but unfortunately
I've decided that I'm not 100% and I will not be able to play
like I have to, to compete at this level.
"I tried to play a little bit yesterday and today to see how it
feels. Unfortunately there were no improvements today ... The
plan is obviously to rest."
Ruud reached the fourth round at Melbourne Park last year before
retiring with an abdominal injury against Andrey Rublev.
The 23-year-old's absence will open up his quarter of the draw,
with 11th seed Jannik Sinner of Italy favourite to reach the
quarter-finals while Andy Murray, Nikoloz Basilashvili and Alex
De Minaur will also see an opportunity to go deeper.
Ruud's withdrawal means the men's draw lost two of the top eight
seeds before they played a match, with world number one Novak
Djokovic deported from Australia after losing a court case to
have his visa cancellation overturned.
(Reporting by Hritika Sharma in Bengaluru; Editing by Peter
Rutherford)
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