Third trial over Zantac cancer claims ends with hung jury
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[August 08, 2024]
By Brendan Pierson
(Reuters) -The third trial over claims that discontinued heartburn drug
Zantac ended in a mistrial on Wednesday when jurors could not agree
about whether pharmaceutical company Boehringer Ingelheim was
responsible for an Illinois man's cancer.
Martin Gross alleged in his lawsuit in state court in Chicago that he
developed prostate cancer from a carcinogenic contaminant called NDMA
found in the drug. His lawyer, Sean Grimsley, said he would take his
case to trial again.
"We continue to believe in our case, in our cause and in our client," he
said.
Boehringer Ingelheim said in a statement that it was "disappointed" that
the jury had not reached a verdict and that "the totality of the
scientific evidence" supports "only one conclusion: Zantac does not
cause any type of cancer."
First approved by U.S. regulators in 1983, Zantac became the world's
best-selling medicine in 1988 and one of the first to top $1 billion in
annual sales. It was sold at different times by Boehringer Ingelheim,
GSK, Pfizer and Sanofi, all of which have faced thousands of lawsuits.
Two such cases previously went to trial, both ending in verdicts for the
defense - one for Boehringer Ingelheim and GSK in May, and the other for
GSK on Monday.
Sanofi has agreed to settle about 4,000 cases against it, while Pfizer
has reportedly agreed to settle more than 10,000. The companies have
also settled some individual cases before trial.

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A bottle of Zantac heartburn drug is seen in this picture
illustration taken October 1, 2019. REUTERS/Brendan McDermid/Illustration/File
Photo
 The majority of the lawsuits are in
Delaware state court, where a judge in June allowed more than 70,000
cases to go forward after rejecting the defendants' bid to keep key
plaintiffs' expert witnesses out of court on the grounds that their
scientific methods were not reliable. The companies are appealing
that ruling.
The litigation began after the U.S. Food and Drug Administration in
2020 asked manufacturers to pull the drug off the market over
concerns that ranitidine, the active ingredient in Zantac and
generic versions of the drug, could degrade into NDMA over time or
when exposed to heat.
The drugmakers have said the cases are meritless. They won a
significant victory in 2022, when a Florida federal judge ruled
against about 50,000 cases, finding that the alleged cancer link was
not supported by sound science. Some of those cases are being
appealed.
(Reporting By Brendan Pierson in New York; Editing by Aurora Ellis
and Diane Craft)
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