Pro Picks: Eagles will beat the
Cowboys by double digits to kick off the NFL season
[September 04, 2025]
By ROB MAADDI
The defending Super Bowl champion Philadelphia Eagles face their
bitter divisional rival in the NFL season opener on Thursday night
in a matchup that’s lost a little luster.
Why?
Micah Parsons won’t be there chasing Jalen Hurts, pursuing Saquon
Barkley and making life difficult for left tackle Jordan Mailata.
The Dallas Cowboys traded the two-time All-Pro pass rusher to the
Green Bay Packers last week following a contract dispute.
Dak Prescott returns for the Cowboys and George Pickens joins CeeDee
Lamb to give them another playmaking wide receiver. But how will the
Cowboys stop Philadelphia’s dynamic offense without Parsons?
Jerry Jones got his run-stuffer in the trade with Green Bay. Maybe
Kenny Clark helps limit Barkley to under 200 yards rushing. If
there’s no pressure on Hurts, he can pick apart the defense throwing
to A.J. Brown, DeVonta Smith and Dallas Goedert.
The Eagles are 8 1/2-point favorites, according to BetMGM Sportsbook.
Pro Picks likes the champs even though Prescott is 9-4 vs.
Philadelphia.
EAGLES: 31-20
Cincinnati at Cleveland
Line: Bengals minus 5 1/2
Joe Burrow and the Bengals need to start better than they have in
the past. He’s 8-11-1 in Weeks 1-4. The Browns are turning to Joe
Flacco while Dillon Gabriel and Shedeur Sanders wait in the wings.
They should be in the mix for the No. 1 pick next season.
Best Bet: BENGALS: 27-16
Las Vegas at New England
Line: Patriots minus 2 1/2
Mike Vrabel’s Patriots face Pete Carroll’s Raiders as both teams
debut new head coaches. Drake Maye has a new playmaker in Stefon
Diggs. QB Geno Smith and rookie RB Ashton Jeanty join TE Brock
Bowers to instantly upgrade Las Vegas’ offense.
UPSET SPECIAL: RAIDERS: 23-20
Kansas City vs. Los Angeles Chargers, in Brazil
Line: Chiefs minus 3
Patrick Mahomes and the Chiefs have something to prove after a
17-win season ending with a lopsided loss to the Eagles in the Super
Bowl. The Chargers drafted running back Omarion Hampton in the first
round to take pressure off Justin Herbert. They were 9-0 when they
had more than 100 yards rushing last season. The Chiefs had the
eighth-best run defense, giving up 101.8 yards per game.
CHIEFS: 26-20
Arizona at New Orleans
Line: Cardinals minus 6 1/2
Kyler Murray has one winning season as Arizona’s starting QB, but
the Cardinals have a chance to compete in the NFC West after an 8-9
season. They were 11-6 against the spread. The rebuilding Saints
under rookie coach Kellen Moore are starting a rebuild.
CARDINALS: 23-17
Carolina at Jacksonville
Line: Jaguars minus 3 1/2
The Liam Coen era begins in Jacksonville. Can he unlock Trevor
Lawrence’s potential? Bryce Young and the Panthers finished up
strong last season. They’re aiming to take another step forward. The
matchup features the NFL’s two worst defenses in 2024.
JAGUARS: 27-20
Tampa Bay at Atlanta
Line: Buccaneers minus 2 1/2
Baker Mayfield and the four-time defending NFC South champion
Buccaneers couldn’t beat the Falcons last season so they’ve got
something to prove. Michael Penix Jr. watched from the sideline as
Kirk Cousins threw for 785 yards and eight TDs vs. Tampa Bay. The
Falcons will feature Bijan Robinson but the Buccaneers were fourth
against the run.
BUCCANEERS: 26-23
New York Giants at Washington
Line: Commanders minus 6
Jayden Daniels and the Commanders are building off a surprise,
impressive run to the NFC championship game. It wasn’t a fluke.
Russell Wilson makes his debut with the Giants, whose strength is
their defensive line.
COMMANDERS: 23-20
[to top of second column] |
Philadelphia Eagles head coach Nick Sirianni talks to reporters
after a preseason NFL football game against the New York Jets in
East Rutherford, N.J., Friday, Aug. 22, 2025. (AP Photo/Yuki Iwamura)
Pittsburgh at New York Jets
Line: Steelers minus 3
Aaron Rodgers faces his former team and the new coach, Aaron Glenn,
who didn’t want him. Justin Fields faces his former team that let
him walk away in free agency.
STEELERS: 20-19
Miami at Indianapolis
Line: Colts minus 1
Daniel Jones makes his first start for the Colts, who have lost 10
of their past 11 season openers. Tua Tagovailoa and the Dolphins aim
to bounce back from a losing season. He could look for Tyreek Hill
often against a defense that was 26th against the pass.
DOLPHINS: 24-17
San Francisco at Seattle
Line: 49ers minus 2 1/2
Brock Purdy, Christian McCaffrey and the 49ers are healthier and
motivated after a disastrous season. They’re still missing key
players and lost several defensive starters. Sam Darnold takes over
for the Seahawks, who missed the playoffs despite winning 10 games.
49ERS: 23-20
Tennessee at Denver
Line: Broncos minus 8
No. 1 overall pick Cam Ward makes his first career start for the
rebuilding Titans. They’re facing a tough defense and a balanced
offense led by Bo Nix.
BRONCOS: 27-13
Houston at Los Angeles Rams
Line: Rams minus 3
C.J. Stroud and the Texans are underdogs in a matchup of 2024
division winners. Matthew Stafford dealt with a back injury in the
preseason and has to face a fierce defense in the opener.
TEXANS: 23-21
Detroit at Green Bay
Line: Packers minus 2 1/2
The 15-win Lions are underdogs in the opener after a disappointing
end to the best season in franchise history. Their dynamic offense
is back together minus offensive coordinator Ben Johnson, who left
to coach the Bears. Parsons elevated the Packers to Super Bowl
contenders. After sitting out the preseason in Dallas, he has to be
careful not to overdo it in his first game.
PACKERS: 24-23
Baltimore at Buffalo
Line: Ravens minus 1 1/2
Lamar Jackson and the Ravens are looking to avenge a playoff loss in
Buffalo in a matchup that should have playoff ramifications from a
home-field advantage standpoint. Reigning NFL MVP Josh Allen and the
Bills have won 10 straight home games. Both teams have failed to
dethrone the Chiefs in recent years and neither will be satisfied
with anything less than a Super Bowl.
BILLS: 26-23
Minnesota at Chicago
Line: Vikings minus 1 1/2
There’s excitement in Chicago surrounding Johnson taking over the
Bears. Can he develop Caleb Williams as he did Jared Goff? J.J.
McCarthy makes his first career start for the talented Vikings, who
are coming off a 14-win season.
Vikings 24-20
___
2024 Record:
Overall: Straight up: 202-83. Against spread: 151-129-5.
Prime-time: Straight up: 44-14. Against spread: 31-26-1.
Best Bet: Straight up: 12-7. Against spread: 11-8.
Upset Special: Straight up: 11-9. Against spread: 11-9.
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