"Sack Vick!" chanted the demonstrators, organized by People for the Ethical Treatment of Animals, as they walked peacefully in front of the Park Avenue building. Many held dogs who had the "Sack Vick" signs on their backs and one woman brought a pit bull, the breed killed in the dogfighting operation the Atlanta quarterback is accused of sponsoring.
Goodell met with officials from the American Society for the Prevention of Cruelty to Animals.
The leaders of the demonstration focused on Goodell's one-year suspension of Tennessee's Adam "Pacman" Jones under the NFL's personal conduct policy, although Jones has not been convicted of any crime.
"We think they should do the same with Michael Vick," said Dan Shannon, an assistant director of campaigns for PETA. "We don't think their 'wait and see' attitude goes far enough. If they suspended Pacman Jones, they can suspend Vick."
After the Vick was indicted Tuesday, the NFL said it would monitor legal developments in the case. Vick is scheduled to be arraigned Thursday in federal court in Richmond, Va.
On Friday, though, NFL spokesman Brian McCarthy said:
"We agree with them that dogfighting is cruel, degrading and illegal. The alleged activities are very disturbing and we are extremely disappointed Michael Vick has put himself in this position.
"We are having extensive dialogue with numerous groups and individuals, including the ASPCA, and are reviewing all of our options to deal with this as quickly as possible."
Sherry Ramsey, a staff attorney for the Humane Society of the United States, said she was disappointed in the league's stance.
"There is a precedent in the Jones suspension," she said.