Ramirez lined a 1-0 pitch from Scott Linebrink (2-2) over the fence in center and the majority of the 41,106 fans
- most of them obviously pulling for the Cubs - went into a frenzy.
The White Sox had a 3-1 lead headed into the seventh before Derrek Lee and Ramirez hit back-to-back homers off reliever Octavio Dotel to tie the game.
It was the first time the two city rivals met as first-place teams since interleague play began in 1997.
A.J. Pierzynski and Jermaine Dye homered for the White Sox.
The two teams met in the 1906 World Series - city fans are envisioning a rematch this season
- with the White Sox winning. Two years later, the Cubs won the World Series and haven't captured another since, a 100-year drought.
The White Sox got a leadoff double from Brian Anderson in the ninth off Kerry Wood (4-1), who then retired the next three batters, striking out an agitated Pierzynski to end the threat. Pierzynski was called out on an appeal to third base umpire Mike Everett and then fired down his helmet and flipped his bat away on his way to the dugout.
That's the kind of emotion this series brings out.
Pierzynski hit a two-run homer in the third off Ted Lilly - his fifth career homer against the Cubs as a member of the White Sox
- to make it 3-1.
White Sox lefty John Danks had shut the Cubs down for six innings, allowing just five hits and a run before giving way to Dotel.
The Cubs didn't look sleepy early on after playing in St. Petersburg, Fla., on Thursday night and not getting back to Chicago until 2 a.m. They scored a run in the first as leadoff hitter Kosuke Fukudome beat out a swinging bunt and moved to third on Ryan Theriot's sharp single to right center. Fukudome scored when Lee hit into a double play.
Dye tied it in the second with his third homer in two games and fifth in the last five, a line drive that sailed over the left field bleachers and onto Waveland Ave.
Danks retired 11 straight before Fukudome's one-out single in the sixth but third baseman Joe Crede took Theriot's grounder and started the White Sox's third double play of the day. Danks went six innings, allowing a run and five hits. Lilly lasted 6 2-3, giving up seven hits and three runs.