Brian Roberts had two hits to extend his hitting streak to 13 games as Baltimore roughed up Jason Marquis, who hadn't lost in his previous seven starts.
The Orioles broke it open with five runs in the third inning, winning the rubber game of their first-ever trip to Wrigley. Milwaukee is the only other team to win a series at the Cubs' home this year.
Marquis (6-4) gave up seven runs and seven hits in four innings for Chicago, which had won seven straight series at Wrigley. He had won his last four starts and hadn't picked up a loss since May 13.
Radhames Liz (2-0) held the Cubs to four hits and two runs in five-plus innings. The rookie walked four and struck out four in just his fifth start this season.
Baltimore scored all of its third-inning runs with two out. Marquis walked Kevin Millar to force in a run before Huff doubled down the right-field line to make it 3-0. Payton added a two-run single.
Nick Markakis hit a two-run double in the fourth for the Orioles, who finished with 13 hits.
Eric Patterson had two RBIs for Chicago.
Notes: Cubs RHP Carlos Zambrano (right shoulder strain) played catch before the game and said he should be ready to throw a bullpen session Sunday. He likely will be activated to start July 4 at St. Louis. ... The Orioles placed RHP Matt Albers on the 15-day DL after he left his spot start Wednesday in the first inning with right shoulder inflammation. Baltimore recalled RHP Fernando Cabrera from Triple-A. ... The Cubs have signed 26 players from the amateur draft, including two of their top five and seven of 10. ... Cubs manager Lou Piniella will replace fired Mets manager Willie Randolph on the NL staff at the All-Star game at Yankee Stadium next month. ... Huff's four hits tied a career high.
[Associated Press]
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