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Facing third-and-6 at the Packers 48 on the first drive of the second half, Manning's pass skimmed off Reggie Wayne's fingertips and landed in the hands of Collins, who rambled 62 yards for a touchdown.
"I think that changed the whole game," Collins said. "That was an opportunity for us to go up 24-7 and just take over the game."
Collins made another big play on the Colts' next possession, breaking up a deep pass that could have gone for a touchdown to wide-open wide receiver Marvin Harrison.
And with the Colts driving in the fourth quarter, Rouse stepped in front of wide receiver Anthony Gonzalez to grab the ball, returning it 99 yards for a touchdown to put the game out of reach.
Along the way, the Packers showed a swagger that had been missing lately.
One particular example came from wide receiver Ruvell Martin, who took a huge hit from Gary Brackett after catching a pass from Rodgers in the second quarter -- but instead of staying down, he bounced right back up and did a little shoulder-shaking celebration dance that reminded Rodgers of something veteran Donald Driver would do.
Grant ran 11 yards up the middle for a touchdown on the next play, putting the Packers ahead 17-7 going into halftime.
Notes: Sunday's game was the Colts' first loss in the month of October since a 2004 game against Kansas City. ... McCarthy said defensive end Jeremy Thompson had a stinger and did not return. ... Rouse's runback ties a record for the longest interception return in team history, set by Tim Lewis in 1984. ... The Packers have six returns for scores this season -- five interception and a punt. ... Packers DL Johnny Jolly blocked a field goal in the third quarter.
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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