The Indians won despite grounding into six double plays, tying an American League record for the 14th time.
Even after trading Cliff Lee, Victor Martinez and Ryan Garko, the Indians continued their recent surge, winning 11 of their last 16 games. Before the game, the Indians traded veteran right-hander Carl Pavano to the Twins.
Indians starter Jeremy Sowers (4-7), who came into the game with a 0-6 record with a 6.31 ERA lifetime against Chicago, hung on for the victory. He pitched seven-plus innings, allowing two runs and six hits. He struck out three and walked two.