Micah Owings (1-0) got the victory with three innings of relief. Francisco Cordero gave up a solo homer by Derrek Lee in the ninth before picking up his first save.
The Cubs had a chance to pull it out in the ninth, when Lee homered with one out. Chicago then loaded the bases with two outs on Kosuke Fukudome's single, third baseman Scott Rolen's fielding error and Mike Fontenot's infield single. Pinch-hitter Chad Tracy hit a check-swing grounder back to Cordero for the final out.
Stubbs, who also tripled, has been one of the Reds' few consistent hitters during the opening week. His first homer of the season broke open a game between two teams struggling to hit.
Right-hander Carlos Silva held the Reds to one run in six innings - Stubbs tripled to open the first, then scored on Orlando Cabrera's sacrifice fly. Silva settled in on a chilly, 54-degree evening, preventing the Reds from rallying until he was out of the game.
Chicago failed to make the most out of a ragged start by Homer Bailey, who went deep in counts and lasted only five innings. The 23-year-old Bailey was trying to extend his sensational closing stretch of 2009, when he had a 1.70 ERA in his last nine starts
- the best in the majors during that span. A little wildness got in the way.
Bailey gave up seven singles in five innings, but also walked two batters, hit two and committed a balk. He needed 106 pitches to get that far, the best sign of how much he struggled.
Aramis Ramirez hit a sacrifice fly, and Xavier Nady and Lee had run-scoring singles off Bailey. Nady got hit by pitches twice in the left arm
- once by Bailey, once by Owings.