It will be several weeks before organizers know if they surpassed the 34,529 who set the record across England in 2007.
But the publicity will help raise money for autism.
The idea started in Ventnor, N.J. Isabelle Mosca said blowing bubbles was a way for her 11-year-old autistic son Kyle to share an activity with his classmates.
In New Jersey, people blew bubbles at schools, Atlantic City casinos, shopping malls and gyms. Participation was expected to be strong in Louisiana after a local country singer publicized the event online.
And participants signed up as far away as Australia once the event went viral on Facebook.