Perez was suspended for 25 games on July 6 when he tested positive for a second time. Under baseball's labor contract, a player who tests positive for the first time is sent for counseling.

Perez has been the only player suspended by baseball for stimulants since they were banned before the 2006 season.

His first suspension had been set to end after Friday night's game against the Chicago White Sox, but Tigers president Dave Dombrowski wouldn't say whether Perez would have been restored to the active roster absent the new positive test.

Under baseball's labor contract, a player cannot be disciplined multiple times for a positive test stemming from the same use of a banned substance, meaning Perez had to take a prohibited stimulant more than once.

Another positive test would lead to a suspension to be determined at the discretion of commissioner Bud Selig, with Perez having the right to have an arbitrator review the penalty.

His initial suspension cost him $396,175, and the second will cost him $792,350 - a total of $1,188,525 of his $2.5 million salary. He will miss the final 54 games of the regular season and finish serving the suspension next year, if he is signed.