The Cubs wasted a bases-loaded threat in the top of the 11th and fell one game behind Milwaukee, which beat Pittsburgh 6-1. Chicago has lost four of its last six.
Down 4-1 early, the Astros rallied and ended a five-game losing streak.
Ryan Dempster (2-6) walked Mark Loretta with one out in the 11th and Eric Bruntlett pinch-ran. Scott followed with his game-winner.
Brad Lidge (4-2) escaped a jam in the 11th by getting Jacque Jones to fly out, stranding three runners.
[Associated Press;
by Chris Duncan]
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