Anthony wasn't bothered by a broken bone in his shooting hand, finishing 5-of-12 from the floor and 9-of-11 from the free throw line. He played with his two middle fingers wrapped in white athletic tape, per doctor's orders.
The Nuggets forward was injured on Jan. 5 when Indiana Pacers center Jeff Foster swatted at the ball, catching a good chunk of Anthony's hand. Anthony sat out 10 games, the team going 6-4 in his absence.
Shortly after being cleared to play Thursday, Anthony received the news he'd been snubbed from the All-Star team.
The Nuggets will be represented by Chauncey Billups, who will be making his fourth straight appearance after being named a Western Conference reserve.
Billups finished with 12 points and six assists against Charlotte.
Raja Bell led the Bobcats with a season-high 27 points, while Boris Diaw added 16 and former Nuggets player Juwan Howard had 11.
Nene continues his run of torrid shooting, hitting eight straight before finally missing a layup late in the third quarter.
The Brazilian forward ranks among the best in the league in field goal percentage this season. He hit all 12 shots he attempted against Utah last Sunday, tying a team record for the most makes without a miss.
The Nuggets led by as many as 20 points in the fourth quarter, before removing their regulars and coasting to their fourth win in five games.
Denver is now 4-1 all-time against Charlotte at home.
Bobcats coach Larry Brown enjoys his jaunts back to the Mile High City, where he used to coach the Nuggets in the
'70s while they were in the ABA, then the NBA. His 251 wins is still second on Denver's all-time coaching list.
However, Brown hasn't fared well this season against teams he used to coach, dropping to 4-10.
Bobcats forward Gerald Wallace was released from a Los Angeles hospital after being treated for a partially collapsed lung he sustained on a flagrant foul against the Lakers earlier this week.