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 Contreras (4-7) is 4-2 since being recalled from the minors on June 8 and beat the Indians for the second time in a week. He allowed six hits, walked one and struck out nine.
Jhonny Peralta's sixth homer of the season ended Contreras' shutout bid in the seventh. After Travis Hafner and Ryan Garko followed Peralta's homer with consecutive singles, Matt Thornton relieved and got pinch-hitter Jamey Carroll to hit into a double play.
Dye had an RBI double in the first inning and a run-scoring single in the third off Aaron Laffey (3-2) and singled home another run in the seventh off Jose Veras.
Laffey, who strained his right oblique on May 22, was activated from the disabled list before the game. He allowed seven hits and four runs in six innings.
Chicago got a run in the first when Alexei Ramirez singled and raced home on Dye's double into the left-field corner.
The White Sox tacked on three in the third when they had four straight hits. Scott Podsednik walked and Ramirez singled before Dye and Paul Konerko followed with RBI singles to make it 3-0. Another single by Jayson Nix loaded the bases and Gordon Beckham's sacrifice fly put Chicago ahead by four.
Contreras struck out six of the first nine batters he faced, including the side in the second inning. After getting two singles in the first, Cleveland didn't manage another hit until Asdrubal Cabrera's infield single off Beckham's glove at third base in the sixth.
Victor Martinez snapped an 0-for-15 skid with a first-inning single. With runners at first and second and one out, Contreras fanned Shin-Soo Choo before Peralta grounded into a forceout.
NOTES: The Indians have lost 17 of 22. ... Martinez is 2 for 34 over his last 10 games. ... The game-time temperature was only 63 degrees on a damp night ... White Sox LF Carlos Quentin, who is on a rehab assignment at Triple-A Charlotte, might not be ready until after the All-Star break. Quentin is suffering from plantar fasciitis and is still not running at full speed, manager Ozzie Guillen said. ... One night after his three-homer, seven-RBI performance, Konerko went 2 for 4 with two singles and an RBI.
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