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With the bases loaded and two outs in the seventh, Boesch hit a routine fly.
Dirks finally added an insurance run with his homer to right.
The 26-year-old Axelrod made his first start of the season for the White Sox, part of a pitching shuffle that moved Chris Sale from starter to closer. Axelrod struck out four and walked two.
Chicago outfielder Dayan Viciedo left in the seventh after being hit in the right elbow with a pitch.
NOTES: Chicago manager Robin Ventura said the White Sox will bring up LHP Eric Stults from the minors to start the second game of Monday's doubleheader at Cleveland. Stults (0-0) will face Josh Tomlin (1-2). Chicago RHP Phil Humber (1-1) faces Zach McAllister (0-0) in the opener. ... Detroit RHP Doug Fister (0-0) returns from a left side strain to make his second start of the season Monday night at Seattle. Blake Beavan (1-3) takes the mound for the Mariners. ... Dunn's homer was his 374th, tying Rocky Colavito for 69th on the career list. ... Leyland earned his 1,602nd win, tying Fred Clarke for 16th on the career list.
[Associated Press;
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