Meredith Kercher's relatives made their first comments since a jury in Perugia, Italy, announced early Saturday that they had convicted Knox and sentenced her to 26 years in prison for the 2007 murder.
The court also convicted Knox's co-defendant and former boyfriend, Italian Raffaele Sollecito, and gave him a 25-year jail term. The two reportedly both were under suicide watch in separate prisons.
"Ultimately we are pleased with the decision, pleased that we've got a decision, but it's not a time for celebration," Lyle Kercher, the victim's brother, said.
Kercher's sister, Stephanie, said the verdict "does bring a a little bit of justice, for us and for her." But she added: "Life will never be the same without Mez."
Kercher, 21, was Knox's roommate while they studied in Perugia.
Her body was found in a pool of blood with her throat slit on Nov. 2, 2007, at the apartment they shared. Prosecutors said the Leeds University student was murdered the previous night.
After a yearlong trial and some 13 hours of deliberations, the jury read out the verdict in a packed courtroom shortly after midnight. Knox burst into tears and murmured "No, no," clinging to one of her lawyers.
Minutes later, the 22-year-old from Seattle was put in a police van with sirens blaring and driven back to her jail just outside Perugia.
She spent her first night in jail as a convicted woman under suicide watch, the ANSA news agency and other reports said. Sollecito, also kept under suicide watch
- which is common in such cases - received the visit of one of his lawyers, ANSA said.
In Italy verdicts can be appealed by both sides. The prosecutors said they were satisfied with the ruling and would not seek to appeal, even though the court did not grant their request for life imprisonment. Prosecutor Manuela Comodi said that the verdict "recognizes the defendants are guilty of all the crimes they had been charged with."
Both the Knox family and lawyers for Sollecito have announced an appeal.
The American's father, Curt Knox, asked shortly after the verdict if he would fight on for his daughter, replied, with tears in his eyes: "Hell, yes."
Throughout the trial, prosecutors depicted Knox as a promiscuous and manipulative she-devil whose personality clashed with her roommate's. They say Knox had grown to hate Kercher.