Ali Akbar Salehi, who also heads the nuclear program, told the official IRNA news agency that Iran needs the sites to generate 20,000 megawatts of electricity through nuclear power plants over the next 20 years.
The statement comes at a time of heightened Western concerns over Iran's nuclear intentions. President Mahmoud Ahmadinejad has said Iran is considering whether to scale back cooperation with the International Atomic Energy Agency after it approved a resolution censuring Iran over its nuclear program.
Tehran argues its nuclear program is peaceful and insists it has a right to enrich uranium to produce fuel for nuclear reactors to generate electricity. The United Nations has demanded Iran freeze enrichment.
Iran and the West are deadlocked over a U.N. proposal for Iran to send much of its enriched uranium abroad. The plan is aimed at drastically reducing Iran's stockpile of enriched uranium in hopes of thwarting the country's ability to potentially make a nuclear weapon. So far, Iran has balked at the offer.
Last week, Tehran announced it intends to build the 10 new sites - a statement that followed a strong rebuke from the Vienna-based IAEA.
It was not clear when or whether the government will approve the construction. But Iran's decision to dramatically expand its uranium enrichment program and scale back cooperation with the IAEA is widely seen as a slap to Western efforts to curtail Iran's nuclear program.